The following paper is scheduled to appear in the forthcoming issue of the Journal of Integrative Neuroscience, volume 1, Issue 2, December 2002: AN INTEGRATIVE THEORY OF COGNITION A framework is outlined for connecting brain imaging activity with the underlying biophysical properties of neural networks, and their mechanisms of action and organizing principles. The main thrust of the framework is a dynamic theory of semantics based on functional integration of biophysical neural networks. It asserts that higher-brain function arises from both synaptic and extrasynaptic integration in the neuropil where information on environmental changes are represented dynamically through a discourse of semantics. Consequently, integrative neural modeling is shown to be an important methodology for analyzing the response activities of functional imaging studies in elucidating the relationship between brain structure, function and behavior. Roman R. Poznanski Centre de Recherche en Physiologie Integrative Hopital Tarnier CHU Cochin-Port-Royal, 89, rue d'Assas, Paris 75006 FRANCE [log in to unmask] Other papers appearing are: CONTROLLER-REGULATOR MODEL OF THE CENTRAL NERVOUS SYSTEM by Masao Ito, Director of Brain Science Institute, RIKEN, Japan NEUROINFORMATICS: THE INTEGRATION OF SHARED DATABASES AND TOOLS TOWARDS AN INTEGRATIVE NEUROSCIENCE by Gary F. Egan, Howard Florey Institute for Experimental Physiology and Medicine, Melbourne, Australia. and more! ----------------------------- The Journal of Integrative Neuroscience will serve as a focus for new discoveries in the advancement of experimental and theoretical neuroscience. The journal covers the following disciplines: 1. PDE's and nonlinear dynamical systems; 2. Noninformationalist/noncomputationalist theories of mind; 3. Integrative neural modeling; 4. Functional imaging (PET/fMRI); 5. Experiments linking molecular with cellular phenomena. 6. Interregional functional connectivity (anatomy and physiology); 7. Philosophical foundations of neuroscience; 8. Neural engineering applications. Computational neuroscience with its computer metaphors provides little help to foundational theory because of its lack of relation to physical law and its weak relationship to neurobiological processes. The new field of integrative neuroscience encompasses the requirements of physical-biological foundations, expansive inclusiveness of scope across biological and psychological variables, multi-leveled hierarchical complexity, and analytical tools demanded by the brain's complexity. Integrative neuroscience is a large-scale synthesis whose scope and time are right. It embodies the future directions of theoretical neuroscience, and should provide many bridging recognitions. http://www.worldscinet.com/jin/mkt/editorial.shtml (Only vol. 1, issue 1 is free). For orders within Europe, please contact the Imperial College Press sales department at: Tel: +44 (0)20 7836-0888 Fax: +44 (0)20 7836-2020 during U.K. business hours. Outside Europe, our books and journals are distributed by World Scientific Publishing Co.: 5 Toh Tuck Link, SINGAPORE 596224 Fax: 65-6467-7667 Tel: 65-6466-5775 E-mail: [log in to unmask] Price Information: ISSN: 0219-6352 ; Vol. 1/2002; 2 Issues Special Rates: Individuals (Print Only) US$56 Institutions/Libraries US$ 84 --------------------------